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Targeting Rank1 protein towards the cure of Osteomyelitis using small molecule inhibitors
Anushka Ivatury and Divya Ramamoorthy
The study targets RANKL using small molecule inhibitors in order to mitigate bone resorptions and protect immune health. Through protein preparation, ligand optimization, and molecular docking, we were able to analyze different small molecular inhibitors as well as antiviral compounds. Looking for molecular inhibitors and antiviral compounds with topmost docking scores, our results indicated S1774 to be a potential inhibitor with a docking score of -5.035 kcal/mol. In the end, we identified possible inhibitors to mitigate a bone disease like osteomyelitis.

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